1α,25-Dihydroxy Vitamin D3 Calcitriol Cas 32222-06-3
|Terms of Trade:||CIF|
|Min. Order:||1 Kilogram|
|Delivery Time:||15 Days|
|Place of Origin:||CHINA|
|Supply Ability:||TRUE MANUFACTURER|
Model No.: 32222-06-3
Calcitriol cas number is 32222-06-3,which is one of the most important metabolically active products of Vitamin D3 in the human body. It can promote the absorption of calcium in the intestine and regulate the calcification of bone. Calcitriol was launched in 1978 under the trade name "Rocaltrol" for the treatment of postmenopausal osteoporosis, chronic renal insufficiency, postoperative hypothyroidism, idiopathic hypoparathyroidism, and pseudohypothyroidism. vitamin D-dependent rickets, hypophosphatemic vitamin D resistant rickets. Because calcitriol is an endogenous substance that is effective, safe, and stable, It has been clinically used for osteoporosis in Japan, New Zealand, Australia, Italy, and the United Kingdom for decades. It is listed by the World Health Organization as one of the drugs of choice for the treatment of osteoporosis.
Calcitriol cas number 32222-06-3 is present in healthy people and is the most important active product of vitamin D3 metabolism in the body. Vitamin D3 has more than 40 kinds of metabolites, and the main bioactive activity is calcitriol, which acts by binding to vitamin D receptors on the nucleus of target organ tissues. Calcitriol has a different effect on different target tissues. In vitro experiments have shown that calcitriol has the effect of promoting bone formation and increasing the amount of metastatic growth factor beta, which is an important factor in stimulating the proliferation and differentiation of osteoblasts. High-dose calcitriol promotes osteoclast differentiation in vitro, inhibiting bone absorption in the body by increasing calcium absorption and inhibiting the secretion of parathyroid hormone. In the parathyroid glands, calcitriol acts directly on parathyroid cells and inhibits the secretion of parathyroid hormone.
Calcitriol cas 32222-06-3 has the following properties: Calcitriol is a white or off-white crystalline compound naturally occurring in humans; it is almost insoluble in water, soluble in organic solvents, and sensitive to air, light and heat. Since calcitriol is hardly soluble in water and difficult to prepare, the main forms of preparation of calcitriol are soft capsules and capsules. Calcitriol has a high physiological activity, a single dose is very small, the general therapeutic dose is only 0.25μg / day -1.0μg / day, in comparison with other oral solid dosage forms, calcitriol is dissolved in a suitable fat-soluble matrix It is prepared into a soft capsule, which can ensure uniform and accurate loading, small dose error, and stable dosage per patient, thus ensuring efficacy and preventing side effects.
Thera. Category:Psoriasis vulgaris
Synonyms: (1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol;1,25-Dihydroxyvitamin D3
Molecular Formula: C27H44O3
Molecular Weight: 416.329
Packing: Export worthy packing
Material Safety Data Sheet: Available on request
Taizhou Volsen Chemical Co., Ltd.
Taizhou Volsen Chemical Co., Ltd. is professional in R&D, producing and marketing Pharmaceutical raw materials, pharmaceutical intermediates in China. VOLSEN consists of about 100 experienced employees including 3 PhD and 10 Master, and 35000 sqm facilities including research laboratories, kilo lab, pilot plant and full manufacturing plant,
VOLSEN R&D specialists, quality manager and sales with abundance experience make sure products are reliable and service is professional. The producing person inspect every step of the whole process and check up the quality strictly, in order to insure every batch of raw material achieve the standard of EP,CP, JP,BP etc.Matching to the diversified requirements of companies VOLSEN is steadily marching to reach the peaks.
Volsen owns a professional custom synthesis department, with more than 15 senior scientific research chemical personnels who have a graduate degree or above. We also have an independent scientific management system. Our company integrates years of production experiences and talent reserves that forms a strong R&D production capacity, furthermore we could undertake various chemicals customizations from kg to ton relying on the existing production base and equipment.
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- Company Name: Taizhou Volsen Chemical Co., Ltd.
- Representative: Mr Chen
- Product/Service: Favipiravir Intermediates , Arbidol Intermediates , Relugolix Intermediates , Vilanterol Intermediates , Remdesivir Intermediates , Umeclidinium Bromide
- Capital (Million US $): 60000000RMB
- Year Established: 2002
- Total Annual Sales Volume (Million US $): Above US$100 Million
- Export Percentage: 91% - 100%
- Total Annual Purchase Volume (Million US $): Below US$1 Million
- No. of Production Lines: 5
- No. of R&D Staff: 91 -100 People
- No. of QC Staff: 11 -20 People
- OEM Services Provided: yes
- Factory Size (Sq.meters): 30,000-50,000 square meters
- Factory Location: Dongying Economic Development Zone , Dongying, Shandong,China
- Contact Person: Ms. Amy Cheng
- Tel: 86-576-88869393
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